COPE antibody

Catalog No. ABIN7112910

This anti-COPE antibody is a Rabbit Polyclonal antibody detecting COPE in WB, ELISA, IHC and IF. Suitable for Human.

Quick Overview for COPE antibody (ABIN7112910)

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-COPE Antibody

Purpose: COPE antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: coatomer protein complex, subunit epsilon

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for COPE

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Alternative Name: COPE

Background:

Synonyms: Coatomer subunit epsilon|Epsilon-coat protein (Epsilon-COP)|COPE

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors(ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity).

Molecular Weight: 36 kDa

Gene ID: 11316

UniProt: O14579